carmustine (bis-chloroethylnitrosourea, bcnu, bicnu) is a medication used mainly for chemotherapy. it is a nitrogen mustard ß-chloro-nitrosourea compound used as an alkylating agent.

description
carmustine is an orange-yellow solid medication used mainly for chemotherapy. it is a nitrogen mustard ß-chloro-nitrosourea compound.

mechanism of action
as an alkylating agent, carmustine can form interstrand crosslinks in dna, which prevents dna replication and dna transcription.[citation needed]

uses
carmustine is used as an alkylating agent to treat several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma), multiple myeloma, and lymphoma (hodgkin's and non-hodgkin).

bcnu is sometimes used in conjunction with alkyl guanine transferase (agt) inhibitors, such as o6-benzylguanine. the agt-inhibitors increase the efficacy of carmustine by inhibiting the direct reversal pathway of dna repair, which will prevent formation of the interstrand crosslink between the n1 of guanine and the n3 of cytosine.

it is also used as part of a chemotherapeutic protocol in preparation for hematological stem cell transplantation, a type of bone marrow transplant, in order to reduce the white blood cell count in the recipient. use under this protocol, usually with fludarabine and melphalan, was developed by oncologists at the university of texas md anderson cancer center.[citation needed]

Дрессировка собак в вашем городе! Заходите на наш сайт https://nsdog.ru и заказывайте услуги по дрессировке в вашем городе! Мы работаем по всей москве и московской области. Пользователям данного сайта предлагаем купон на скидку в 10% на первое занятие с собакой! Promo code: d22825bc52f0fbb340c9f0259ae6974c

Повторять одну и ту же команду несколько раз. [url=https://nsdog.ru]https://nsdog.ru[/url] Помните, никогда не разрешайте щенку того, что взрослой собаке будет запрещено. Я не кинолог, никогда им не был и у меня нет кинологического образования.

This year turned out to be very difficult. But we have optimized and reduced the cost of our products!
It is almost impossible to find prices lower than ours, the sale is at the cost price level.
Watch and be surprised by our super low prices https://cutt.us/6nChw

Hello
Best offer 2021 https://is.gd/OUL6yh

mys604224utr WzoLEFl f0Ur o3C1vz1

mes604224uttjr OSkNiv6 takP P3ESx2c

mns604224uttjr 8Vmgcs6 h0JV 8AEiyUF

Good whatever time of day it is where you are!

Sending newsletters of Your commercial offers via contact forms to the sites of business organizations via all countries and domain zones of the world.

website =» xn----7sbb1bbndheurc1a.xn--p1ai

The Letter is sent to email address of firm one hundred percent will get to inside of the inbox folder!

4000 bases:
Price List =» xn----7sbb1bbndheurc1a.xn--p1ai/prajs-list/

Test:
twenty thousand messages on foreign zones to your E-mail - 20 $.
We need from You only E-mail, title and text of the letter.

In our price list there are more 800 databases for all domain zones of the world.
Common databases:
All Europe 44 countries 60726150 of sites - 1100$
All European Union 28 countries 56752547 of domains- 1000$
All Asia 48 countries 14662004 of domains - 300$
All Africa 50 countries 1594390 of sites - 200$
All North and Central America in 35 countries 7441637 of domains - 300$
All South America 14 countries 5826884 of domains - 200$
New domain names from around the world registered 24-48 hours ago. (A cycle of 15 mailings during the month) - 500$
Companies and Enterprises of Russia 4025015 - 300$
Ukraine 1114526 of sites - 100$
All Russian-speaking countries minus Russia are 14 countries and there are 1979217 of domains - 200$
New sites of the RF, registered 24-48 hours ago (A cycle of 15 mailings during the month) - 250$

Databases:
Whois-service databases of domains for all countries of the world.
You can purchase our databases separately from newsletter's service at the request.

P/S
Please, do not respond to this commercial offer from your email account, as it has been generated automatically and will not reach us!
Contact Feedback form =» xn----7sbb1bbndheurc1a.xn--p1ai/to-order/

PRICE LIST:

Test mailing: $20 – 20000 contact forms websites

All Europe 44 countries there are 60726150 websites – $1100

All EU 28 countries there are 56752547 websites – $1000

All Asia 48 countries there are 14662004 websites – $500

All Africa 50 countries there are 1594390 websites – $200

All North and Central America is 35 countries there are 7441637 websites – $300

All South America 14 countries there are 5826884 websites – $200

Top 1 Million World’s Best websites – $100

Top 16821856 the most visited websites in the world – $300

New websites from around the world registered 24-48 hours ago. (A cycle of 15 mailings during the month) – 500$

Businesses and organizations of the Russian Federation – there are 4025015 websites – $300

All Russian-speaking countries minus Russia – there are 14 countries and 2440822 websites – $200

New websites of the Russian Federation, registered 24-48 hours ago. (A cycle of 15 mailings during the month) – 250$

1499203 of hosting websites around the world (there are selections for all countries, are excluded from databases for mailings) – $150

295285 websites of public authorities of all countries of the world (selections for all countries, are excluded from databases for mailings) – $100

3516251 websites online stores Worldwide – $250

CMS mailings:

3dCart 14689 websites - $50
Adobe CQ5 133567 websites - $80
Advance 17589 websites - $50
AdVantShop.NET 2453 websites - $30
ALMA 7095 websites - $30
Ametys 2389 websites - $30
Amiro 29587 websites - $30
Angora 20357 websites - $50
AVS 1369 websites - $30
BbPress 1487 websites - $30
BESTWEB 2699 websites - $30
BigCommerce 78257 websites - $50
Bitrix 319687 websites - $80
Blogger 658267 websites - $80
Blogspot 279865 websites - $80
BuddyPress 51477 websites - $50
Burning Board 4659 websites - $30
Catalyst Web 11689 websites - $50
ClassiPress 11796 websites - $50
CMSimple 11052 websites - $30
Concrete5 72100 websites - $50
Contao 110897 websites - $80
CONTENIDO 5069 websites - $30
Convio 2268 websites - $30
Coppermine Photo 1296 websites - $30
CS Cart 11400 websites - $30
Datalife Engine 42587 websites - $50
Dede 230589 websites - $100
DedeEIMS 96068 websites - $50
DIAFAN 4058 websites - $30
Discuz 47962 websites - $50
Django 71167 websites - $50
DokuWiki 9588 websites - $30
Dotnetnuke 82964 websites - $50
Drupal 978298 websites - $100
EasyBlog 1165978 websites - $100
EPiServer 29876 websites - $50
ExpressionEngine 1769823 websites - $150
eZ Publish 5367 websites - $30
F- 9356 websites - $30
FireBoard 1567 websites - $30
General Blogs 2067 websites - $30
GetSimple 23094 websites - $50
Host 6871 websites - $30
HostCMS 5042 websites - $30
HubSpot 31762 websites - $50
i- 9438 websites - $30
Image 1368 websites - $30
InSales 14149 websites - $50
InSales 11081 websites - $30
InstantCMS 4136 websites - $30
InteractiveBBS 32367 websites - $50
Invision Power Board 2430 websites - $30
IPBoard 2266 websites - $30
IT 15189 websites - $50
jforum 1056 websites - $30
jobberBase 3387 websites - $30
Joomla K2 154367 websites - $80
Joomla 1906994 websites - $200
Koobi 3722 websites - $30
Liferay 5137 websites - $30
Made Simple 20567 websites - $50
Magento 369447 websites - $80
MediaMaxScript 103896 websites - $80
MediaWiki 41468 websites - $50
Microsoft SharePoint 13198
MODx 64023 websites - $50
Moodle 8195 websites - $30
Movable Type 13096 websites - $50
MyBB 4367 websites - $30
myUPB 3397 websites - $30
NetCat 7294 websites - $30
NG 18356 websites - $50
NING 3687 websites - $30
NopCommerce 18600 websites - $30
Open 5916 websites - $30
OpenCart 667000 websites - $80
Osclass 4652 websites - $30
osCommerce 68468 websites - $50
OUR- 3096 websites - $30
OXID eShop 12200 websites - $50
Oxwall 6800 websites - $30
Parallels Plesk Sitebuilder 174216 websites - $80
php 14367 websites - $50
php Link 2298 websites - $30
phpBB 24400 websites - $30
PHP-Fusion 2596 websites - $30
PHPMelody 2365 websites - $30
PHP-Nuke 2489 websites - $30
PHPShop 2667 websites - $30
PHPWeb 29789 websites - $50
PHPWind 4032 websites - $30
Plone 84962 websites - $50
PowerEasy 1697 websites - $30
Prestashop 434100 websites - $80
Question2Answer 5598 websites - $30
R 296498 websites - $80
ReadyScript 6487682 websites - $80
S.Builder 394367 websites - $80
Shopify 6093709 sites websites - $400
Shoutbox 145564 websites - $80
SilverStripe 31721 websites - $50
Simpla 17429 websites - $50
Sitecore 74861 websites - $50
Sitefinity 4183 websites - $30
SMF 8111 websites - $30
SocialGO 54267 websites - $50
SPIP 28269 websites - $50
Squarespace 1098231 websites - $100
StoreLand 8257 websites - $30
SupeSite 12367 websites - $50
Textpattern 10900 websites - $30
TikiWiki 1446 websites - $30
Tilda 47396 websites - $50
Tumblr 302357 websites - $80
TYPO3 845009 websites - $80
Umbraco 146064 websites - $80
UMI.CMS 13191 websites - $50
VamShop 1737 websites - $30
vBulletin 14460 websites - $30
Volusion 16006 websites - $50
WallpaperSiteScript 2811 websites - $30
Weebly 191753 websites - $80
Wix 3379081 sites websites - $250
WooCommerce 4459525 websites - $310
Wordpress 35354537 websites - $650
XenForo 21105 websites - $30
XOOPS 20467 websites - $50
XpressEngine 8565 websites - $30
Zen Cart 26524 websites - $30

Country:

.ae 200462 websites UAE - $50
.ae 1820 websites International zone UAE:.com .net .biz .info .name .tel
.ag 11931 websites Antigua and Barbuda - $50
.ai 33130 websites Anguilla - $50
.am 21995 websites Armenia - $50
.am 1684 websites International zone Armenia:.com .net .biz .info .name .tel
.ar 782608 websites Argentina - $80
.ar 75496 websites International zone Argentina:.com .net .biz .info .name .tel .mobi .asia-$50
.ar.com 135 websites - $30
.at 1356722 websites Austria - $100
.at 181907 websites International zone Austria :.com .net .biz .info .name
.au 2432174 websites Australia - $150
.au 461279 websites International zone Australia:.com .net .biz .info .name
.az 17855 websites Azerbaijan - $50
.az 2036 websites International zone Azerbaijan:.com .net .biz .info .name .tel .mobi .asia-$30
.ba 15725 websites Bosnia and Herzegovina - $30
.ba 2291 websites international zone Bosnia and Herzegovina:.com.net.biz.info.org.name.tel.mobi.asia-$30
.be 1349658 websites Belgium - $100
.be 1056248 websites International zone Belgium:.com .net .biz .info .name
.bg 54418 websites Bulgaria - $50
.bg 50685 websites International zone Bulgaria:.com .net .biz .info .name
.bo 2602 websites Bolivia - $30
.bo 29415 websites International zone Bolivia:.com .net .biz .info .name .tel .mobi .asia-$50
.br 3205100 websites Brazil - $200
.br 1230078 websites International zone Brazil:.com .net .biz .info .name .
.by 99148 websites Belarus - $50
.by 1574 websites International zone Belarus:.com .net .biz .info .name .tel
.ca 2587463 websites Canada - $150
.ca 288395 websites International zone Canada:.com .net .biz .info .name
.cc 436396 websites - $80
.cc 1920589 websites Cocos Keeling Islands- $150
.cf 2461460 websites Central African Republic - $150
.cg 526 websites Congo - $30
.ch 1629450 websites Switzerland - $100
.ch 205292 websites International zone Switzerland:.com .net .biz .info .name .tel .mobi .asia-$50
.ci 5794 websites Cote d'Ivoire - $30
.ci 112 websites International zone Cote d'Ivoire:.com .net .biz .info .name
.cl 590401 websites Chile - $80
.cl 65996 websites International zone Chile:.com .net .biz .info .name .tel .mobi .asia-$50
.cm 29221 websites Cameroon- $50
.cn 23160610 websites China - $600
.cn 1372416 websites International zone China:.com .net .biz .info .name .tel .mobi .asia-$100
.co 1878923 websites Colombia - $100
.co 10854 websites International zone Colombia:.com .net .biz .info .name .tel .mobi .asia-$30
.cx 15753 websites Christmas Island - $50
.cy 11092 websites Cyprus - $50
.cy 744 websites International zone Cyprus:.com .net .biz .info .name .tel .mobi .asia-$30
.cz 1001208 websites Czech Republic - $100
.cz 193400 websites International zone Czech Republic:.com .net .biz .info .name .tel .mobi .asia-$50
.de 15078512 websites Germany - $350
.de 3894156 websites International zone Germany:.com .net .biz .info .name .tel .mobi .asia-$150
.dk 1319155 websites Denmark - $100
.dk 148164 websites International zone Denmark:.com .net .biz .info .name .tel .mobi .asia-$50
.dm 23318 websites Dominica - $50
.dn.ua 1835 websites - $30
.do 5255 websites Dominican Republic- $30
.dy.fi 1112 websites - $30
.dz 5382 websites Algeria - $30
.ec 11731 websites Ecuador - $50
.ec 2897 websites International zone Ecuador:.com .net .biz .info .name .tel .mobi .asia-$30
.ee 131791 websites Estonia- $50
.ee 10490 websites International zone Estonia:.com .net .biz .info .name .tel .mobi .asia-$30
.es 1509048 websites Spain - $100
.es 683845 websites International zone Spain:.com .net .biz .info .name .tel .eu 3046076 websites Europe - $150
.eu 633384 websites International zone Europe:.com .net .biz .info .name .fi 361111 websites Finland - $80
.fi 69631 websites International zone Finland:.com .net .biz .info .name .fr 2810983 websites France - $150
.fr 639546 websites International zone France:.com .net .biz .info .name .ge 24598 websites Georgia - $50
.ge 1676 websites International zone Georgia:.com .net .biz .info .name .tel .gf 996 websites French Guiana - $30
.gg 10528 websites Guernsey islands - $50
.gh 703 websites Ghana - $30
.gi 981 websites Gibraltar - $30
.gp 2044 websites Guadeloupe - $30
.gq 2027422 websites Equatorial Guinea - $100
.gr 327215 websites Greece - $80
.gr 57984 websites International zone Greece:.com .net .biz .info .name .tel .mobi .asia-$150
.gt 15351 websites Guatemala - $50
.hk 116093 websites Hong Kong - $50
.hm 335 websites Heard & McDonald islands - $30
.hn 4732 websites Honduras - $30
.hr 75736 websites Croatia - $50
.hr 16592 websites International zone Croatia:.com .net .biz .info .name .tel .mobi .asia
.ht 1299 websites Haiti - $30
.hu 53940 websites International zone Hungary:.com .net .biz .info .name .tel .mobi .asia-$50
.ie 209620 websites Ireland - $50
.ie 49861 websites International zone Ireland:.com .net .biz .info .name .il 196266 websites Israel - $80
.il 38537 websites International zone Israel:.com .net .biz .info .name .tel .in 1157482 websites India - $100
.in 266179 websites International zone India:.com .net .biz .info .name .tel .io 496216 websites British Indian Ocean - $80
.iq 2401 websites Iraq - $30
.ir 574258 websites Iran - $80
.ir 15487 websites International zone Iran:.com .net .biz .info .name .tel .mobi .asia
.it 2410105 websites Italy – $150
.it 954040 websites International zone Italy:.com.net.biz.info.org.name.tel.mobi.asia-$100
.je 3016 websites Ireland - $30
.jp 1825219 websites Japan - $150
.jp 4683252 websites International zone Japan:.com.net.biz.info.org.name.tel.mobi.asia-$200
.jp.net 5170 websites - $30
.ke 14677 websites Kenya - $50
.kg 10350 websites Kyrgyzstan - $30
.kg 664 websites International zone Kyrgyzstan:.com .net .biz .info .name .tel .mobi .asia-$30
.ki 79 websites Kiribati - $30
.kn 3211 websites Saint Kitts and Nevis - $30
.kr 272463 websites Korea- $80
.kw 484 websites Kuwait - $30
.ky 5783 websites Cayman Islands - $30
.kz 113180 websites Kazakhstan - $80
.kz 5876 websites International zone Kazakhstan:.com .net .biz .info .name .tel .mobi .asia-$30
.lc 1121 websites Saint Lucia - $30
.lk 32654 websites Sri Lanka - $30
.lt 137666 websites Lithuania- $50
.lt 27710 websites International zone Lithuania:.com .net .biz .info .name .tel .mobi .asia- $50
.lu 74322 websites Luxembourg - $50
.lu 4125 websites International zone Luxembourg:.com .net .biz .info .name .tel .mobi .asia-$30
.lv 86593 websites Latvia - $50
.lv 8887 websites International zone Latvia:.com .net .biz .info .name .tel .mobi .asia-$30
.ma 59103 websites Morocco - $50
.mc 3046 websites Monaco - $30
.md 16730 websites Moldova - $50
.md 1293 websites International zone Moldova:.com .net .biz .info .name .tel .mobi .asia-$30
.me 761596 websites Montenegro - $80
.me 86897 websites International zone Montenegro:.com .net .biz .info .name .tel .mobi .asia-$50
.mg 3715 websites Madagascar- $30
.mk 13266 websites Macedonia - $50
.ml 2158835 websites Mali - $100
.mn 17044 websites Mongolia - $50
.mq 1112 websites Martinique (French) - $30
.mr 776 websites Mauritania - $30
.ms 7265 websites Montserrat - $30
.mt 1402 websites Malta - $30
.mu 6475 websites Maurifius - $30
.mv 1996 websites Maldives - $30
.mw 8579 websites Malawi - $30
.mx 670901 websites Mexico- $80
.mx 174571 websites International zone Mexico:.com .net .biz .info .name .tel .mobi .asia-$50
.my 143039 websites Malaysia- $50
.na 1094 websites - $30
.nc 3497 websites New Coledonia (French) - $30
.nl 3925784 websites Netherlands - $200
.nl 1019697 websites International zone Netherlands:.com .net .biz .info .name .tel .mobi .asia-$100
.no 620882 websites Norway - $80
.no 74318 websites International zone Norway:.com .net .biz .info .name .tel .mobi .asia-$50
.nu 255161 websites Niue- $50
.nz 593127 websites New Zealand - $80
.om 1701 websites Oman - $30
.pe 83224 websites Peru - $50
.pe 59157 websites International zone Peru:.com .net .biz .info .name .tel .mobi .asia-$50
.pk 44464 websites Pakistan - $50
.pl 1795299 websites Poland - $100
.pl 327587 websites International zone Poland:.com .net .biz .info .name .tel .mobi .asia-$50
.pr 1358 websites Puerto Rico - $30
.pt 263136 websites Portugal - $80
.pt 17691 websites International zone Portugal:.com .net .biz .info .name .tel .mobi .asia-$50
.py 5593 websites Paraguay - $30
.py 653 websites International zone Paraguay:.com .net .biz .info .name .tel .mobi .asia-$30
.re 15089 websites Reunion (French) - $50
.ro 424401 websites Romania - $80
.ro 42046 websites International zone Romania:.com .net .biz .info .name .tel .mobi .asia-$50
.rs 85503 websites Serbia - $50
.ru 5025331 websites Russian - $250
.ru 514668 websites International zone Russian:.com .net .biz .info .name .tel .mobi .asia-$80
.rw 3806 websites Rwanda - $30
.sa 20421 websites Saudi Arabia- $50
.sa 5064 websites International zone Saudi Arabia:.com .net .biz .info .name .tel .mobi .asia - $30
.sc 4442 websites Seychelles- $30
.se 1491677 websites Sweden - $100
.se 293316 websites International zone Sweden:.com .net .biz .info .name .tel .mobi .asia-$50
.sg 150351 websites Republic Of Singapore - $50
.sh 7560 websites Saint Helena - $30
.si 103778 websites Slovenia- $50
.si 12879 websites International zone Slovenia:.com .net .biz .info .name .tel .mobi .asia-$50
.sk 414198 websites Slovakia- $80
.sk 31572 websites International zone Slovakia:.com .net .biz .info .name .tel .mobi .asia-$50
.sm 8897 websites San Marino - $30
.sn 344 websites International zone Senegal:.com .net .biz .info .name .tel .mobi .asia-$30
.sn 4465 websites Senegal - $30
.sr 580 websites Suriname - $30
.sv 8432 websites Salvador- $30
.sx 2901 websites Sint Maarten - $30
.sy 2972 websites Syria - $30
.sz 321 websites Swaziland - $30
.tc 16384 websites Turks and Caicos Islands- $50
.tf 19841 websites French Sauthern Territory - $50
.tg 1230 websites Togo - $30
.th 22368 websites Kingdom Of Thailand- $50
.tj 6874 websites Tajikistan- $30
.tj 34 websites International zone Tajikistan:.com .net .biz .info .name .tel .mobi .asia
.tk 20085806 websites Tokelau - $500
.tl 2748 websites East Timor - $30
.tm 6395 websites Turkmenistan- $30
.tm 44 websites International zone Turkmenistan:.com .net .biz .info .name .tel .mobi .asia
.tr 243347 websites Turkey - $80
.tr 138818 International zone Turkey:.com .net .biz .info .name .tel .mobi .asia -$50
.tt 1017 websites Trinidad & Tobago - $30
.ua 553216 websites Ukraina - $80
.ua 147202 websites International zone Ukraine:.com .net .biz .info .name .tel .mobi .asia-$50
.ug 3806 websites Uganda - $30
.ug 720 websites International zone Uganda:.com .net .biz .info .name .tel .mobi.asia-$30
.uk 5975887 websites United Kingdom - $250
.uk 3304606 websites International zone United Kingdom:.com .net .biz .info .name .tel .mobi .asia-$150
.us 3139563 websites USA - $200
.us 578927 websites International zone USA:.com .net .biz .info .name .tel .mobi .asia-$80
.uy 15571 websites Uruguay - $50
.uy 31812 websites International zone Uruguay:.com .net .biz .info .name .tel .mobi .asia-$30
.uz 38357 websites Uzbekistan - $50
.uz 365 websites International zone Uzbekistan:.com .net .biz .info .name .tel .mobi .asia
.vc 18641 websites Saint Vincent & Grenadines - $50
.ve 14015 websites Venezuela - $50
.ve 2898 websites International zone Venezuela:.com .net .biz .info .name .tel .mobi .asia - $30
.vg 8389 websites Virgin Islands (British) - $50
.vi 109 websites Virgin Islands (US) - $30
.vn 436005 websites Vietnam - $80
.vn 161855 websites International zone Vietnam:.com .net .biz .info .name .tel .mobi .asia - $50
.vu 1051 websites Vanuatu - $30
.wf 1133 websites Wallis & Futuna Islands - $30
.ws 99308 websites Samoa - $80
.ye 18 websites Yemen - $30
.yt 2004 websites Mayotte - $30
.za 1008308 websites South Africa - $100